GSK046 (GSK-046, IBET-BD2)
GSK046 (iBET-BD2, GSK 046, GSK-046) (CAS No.: 2474876-09-8), a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4...
BI-3406
BI-3406 (CAS No.: 2230836-55-0), a highly potent, selective, and orally bioavailable inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM. Synonyms: KRAS and Son of Sevenless 1...
Giredestrant (GDC-9545)
Giredestrant (GDC-9545, CAS No.: 1953133-47-5), an orally active and selective estrogen receptor antagonist, potently competes with Estradiol for binding and induces a conformational change within the ER ligand binding domain. Synonyms: selective estrogen receptor degrader...
Volociximab Biosimilar, Anti-human Integrin α5β1 Antibody | C065P
The cheapest research grade volociximab biosimilar (anti-human integrin α5β1 monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro and in vivo assays for...
Toralizumab Biosimilar, Anti-human CD40L Antibody | C066P
The cheapest research grade toralizumab biosimilar (anti-human CD40L/CD154 monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro and in vivo assays for studying...
Zalutumumab Biosimilar, Anti-human EGFR Antibody | C067P
The cheapest research grade zalutumumab biosimilar (anti-human EGFR monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro and in vivo assays for studying...
Satumomab Biosimilar, Anti-human TAG-72 Antibody | C064P
The cheapest research grade satumomab biosimilar (anti-human TAG-72 monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro and in vivo assays for studying...
Ruplizumab Biosimilar, Anti-human CD40L Antibody | C063P
The cheapest research grade ruplizumab biosimilar (anti-human CD40L/CD40/CD154 monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro and in vivo assays for studying...
Pateclizumab Biosimilar, Anti-human LT alpha (LT-α) Antibody | C060P
The cheapest research grade pateclizumab biosimilar (anti-human lymphotoxin alpha (LT-α) monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro and in vivo assays...
Pascolizumab Biosimilar, Anti-human IL-4 Antibody | C059P
The cheapest research grade pascolizumab biosimilar (anti-human anti-interleukin-4 (IL-4) monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro and in vivo assays for...