Anti-mouse CD40L (CD154) Monoclonal Antibody (Clone: MR1) | PA007452.m1
$150.00 – $900.00
Recombinant Mouse IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
- Details & Specifications
- References
| Catalog No. | PA007452.m1 |
|---|---|
| Product Name | In vivo Grade Recombinant Anti-mouse CD40L (CD154) Monoclonal Antibody, Mouse IgG1 Kappa (Clone: MR1) |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | CD154, Cd40l, Tnfsf5, Cd40lg, CD40 ligand |
| Clone | MR1. |
| Isotype | Mouse IgG1 Kappa. |
| Specificity/Sensitivity | The in vivo grade recombinant mouse monoclonal antibody (clone: MR1) specifically binds to mouse CD154. |
| Applications | ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD154 protein. |
| Form Of Antibody | 0.2 μM filtered solution of 1x PBS. |
| Endotoxin | Less than 1 EU/mg of protein as determined by LAL method. |
| Purity | >95% by SDS-PAGE under reducing conditions. |
| Shipping | The In vivo Grade Recombinant Anti-mouse CD40L (CD154) Monoclonal Antibody, Mouse IgG1 Kappa (Clone: MR1) are shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| Note | Recombinant Mouse IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card. |
Description
PA007452.m1: Recombinant Anti-mouse CD40L (CD154) Monoclonal Antibody(Clone: MR1), Mouse IgG1 Kappa, In vivo Grade
The in vivo grade recombinant anti-mouse CD40L (CD154) Mouse IgG1 Kappa monoclonal antibody was produced in mammalian cells.
References of anti-mouse CD40L (CD154) antibody (Clone: MR1)
1. Requirement for CD40/CD40L Interactions for Development of Autoimmunity Differs Depending on Specific Checkpoint and Costimulatory Pathways.
Voynova, E., et al.ImmunoHorizons. 2018 Jan 23;2(1):54-66. PMID: 30607385; PMCID: PMC6309431
“Specifically, blockade of CD40L with the anti-CD40L mAb, MR1, inhibited autoantibody production and inflammation in thyroid and salivary gland target tissues. Unexpectedly, however, ATD and pSS in PD-1-deficient IFN-γ-/- NOD.H-2h4 (PD-1-/-) mice developed independently of CD40/CD40L interactions…”
For more technical references or data sheets regarding the anti-mouse CD40L (CD154) antibody (Clone: MR1) formats, please contact our scientific support team at message@sydlabs.com.
Anti-mouse CD40L (CD154) Antibody (MR1) from: In vivo Grade Recombinant Anti-mouse CD40L (CD154) Monoclonal Antibody, Mouse IgG1 Kappa (Clone: MR1): PA007452.m1 Syd Labs
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