Catalog No.	PA007509.h1Fs
Product Name	Anti-mouse TIGIT Antibody (Clone: 10A7) | PA007509.h1Fs
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	VSIG9, VSTM3, WUCAM, T-cell immunoreceptor with Ig and ITIM domains, T cell immunoreceptor with Ig and ITIM domains
Clone	10A7.
Isotype	Human IgG1 kappa.
Source/Host	The anti-mouse TIGIT monoclonal antibody (clone: 10A7) was produced in mammalian cells.
Specificity/Sensitivity	The recombinant 10A7 antibody specifically binds to mouse TIGIT protein.
Applications	Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).
Form Of Antibody	0.2 uM filtered solution, pH 7.4, containing 0.09% sodium azide.
Conjugate	Non-conjugated.
Purity	>95% by SDS-PAGE under reducing conditions.
Shipping	The Recombinant Anti-mouse TIGIT Monoclonal Antibody (Clone: 10A7), Human IgG1 Fc Silent Kappa is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, 2 to 8°C as supplied. Do not freeze it.
Note	Recombinant human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Order Offline	Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card.

Description

PA007509.h1Fs: Recombinant Anti-mouse TIGIT Monoclonal Antibody (Clone: 10A7), Human IgG1 Fc Silent Kappa

Recombinant Human IgG1 Monoclonal Antibody with Fc silent mutation.

Background

The 10A7 antibody binds to the TIGIT protein (WUCAM, Vstm3 or VSIG9), a novel immune checkpoint receptor with inhibitory function. TIGIT is expressed on T cells and natural killer (NK) cells, and several human cancers, including melanoma, NSCLC, and colorectal cancer. Similar to PD-1, the TIGIT receptor limits antitumor immune response in cancer.

Syd Labs provides the following in vivo grade recombinant anti-mouse TIGIT monoclonal antibodies:

Recombinant Anti-mouse TIGIT monoclonal antibodies (Clone: 1F4)
Recombinant Anti-mouse TIGIT monoclonal antibodies (Clone: 10A7)

Anti-mouse TIGIT Antibody (10A7) from: Recombinant Anti-mouse TIGIT Monoclonal Antibody (Clone: 10A7), Human IgG1 Fc Silent Kappa: PA007509.h1Fs Syd Labs

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