- Chemicals, Inhibitors, Activators, Antagonists, and Agonists
RTA-408 (Omaveloxolone)
$90.00 – $600.00RTA-408 (CAS No.: 1474034-05-3), a Novel Synthetic Triterpenoid That Binds to Kelch-like ECH-associated Protein 1 (Keap1) and Attenuate Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Degradation. >99% Purity.
Synonyms: Omaveloxolone, Nuclear…
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ND-646
$220.00 – $1,500.00ND-646 (CAS No.: 1434639-57-2), an Orally Bioavailable and Steric Inhibitor of Acetyl-CoA Carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for Recombinant hACC1 and hACC2, Respectively. >99% Purity.
Synonyms:…
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Batefenterol (GSK-961081)
$120.00 – $700.00GSK-961081 (Batefenterol, TD-5959) (CAS No.: 743461-65-6), Novel Muscarinic Receptor Antagonist and β2
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Etoposide phosphate (BMY-40481)
$85.00 – $250.00Etoposide Phosphate (BMY-40481) (CAS No.: 117091-64-2), potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands.
Synonyms: topoisomerase II inhibitor, BMY-40481, BMY40481, BMY 40481
For…
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Glumetinib (SCC244)
$120.00 – $800.00Glumetinib (SCC244) is a highly selective, orally bioavailable, ATP-competitive c-Met inhibitor with an IC50 of 0.42 nM. Glumetinib has greater than 2400-fold selectivity for c-Met over those 312 kinases…
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KB-0742 dihydrochloride (KB0742)
$250.00 – $1,200.00KB0742 (KB-0742, KB 0742) (CAS No.: 2416874-75-2), an orally bioavailable, potent and selective CDK9 inhibitor with an IC50 of 6 nM, highly selective against other CDKs (>60 fold). 99% Chem…
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GSK046 (GSK-046, IBET-BD2)
$150.00 – $800.00GSK046 (iBET-BD2, GSK 046, GSK-046) (CAS No.: 2474876-09-8), a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98…
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BI-3406
$250.00 – $2,500.00BI-3406 (CAS No.: 2230836-55-0), a highly potent, selective, and orally bioavailable inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM.
Synonyms:…
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Giredestrant (GDC-9545)
$400.00 – $2,500.00Giredestrant (GDC-9545, CAS No.: 1953133-47-5), an orally active and selective estrogen receptor antagonist, potently competes with Estradiol for binding and induces a conformational change within the ER ligand binding…
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Volociximab Biosimilar, Anti-human Integrin α5β1 Antibody | C065P
$175.00 – $1,200.00The cheapest research grade volociximab biosimilar (anti-human integrin α5β1 monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in…
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Toralizumab Biosimilar, Anti-human CD40L Antibody | C066P
$175.00 – $1,200.00The cheapest research grade toralizumab biosimilar (anti-human CD40L/CD154 monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro…
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Zalutumumab Biosimilar, Anti-human EGFR Antibody | C067P
$175.00 – $1,200.00The cheapest research grade zalutumumab biosimilar (anti-human EGFR monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in vitro…
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