Biotinylated Anti-human CD4 Antibody (SK3/Anti-Leu 3a, Human IgG1 Fc Silent Kappa)
$45.00 – $90.00
Biotinylated recombinant anti-human CD4 monoclonal antibody (Clone SK3 / Anti-Leu 3a), engineered with a Human IgG1 Fc-silent domain to minimize non-specific background binding to Fc receptors during cell analysis. Features site-directed biotinylation via a C-terminal Avi tag on the heavy chain, with variable regions derived from anti-human CD4 clone (SK3) and expressed in mammalian cells.
- Conjugation & Purity: Biotinylated (Site-directed via C-terminal Avi-tag), > 95% by SDS-PAGE
- Applications: Flow Cytometry (FC) via Streptavidin Conjugates, Cell Isolation, Functional Assays
- Alternative Formats: Unconjugated mouse IgG1, mouse IgG2a, and human IgG1 Fc-silent versions of clone SK3 are also available at Syd Labs and Ushelf.
- Details & Specifications
- References
| Catalog No. | PA007759.h1Fs-b |
|---|---|
| Product Name | Biotinylated Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Human IgG1 Fc Silent Kappa |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Clone | SK3 / Anti-Leu 3a. |
| Isotype | Human IgG1 Fc Silent Kappa. |
| Source/Host | The site-directed biotinylated anti-human CD4 monoclonal antibody (clone: SK3 / Anti-Leu 3a) was produced in mammalian cells. |
| Specificity/Sensitivity | The site-directed biotinylated recombinant SK3 / Anti-Leu 3a antibody specifically binds to human CD4. |
| Applications | Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads. |
| Form Of Antibody | 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives. |
| Conjugate | Biotin-conjugated. |
| Purity | >95% by SDS-PAGE under reducing conditions. |
| Shipping | The SK3 / Anti-Leu 3a antibody is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| Note | Recombinant mouse IgG1 isotype controls and Recombinant human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card. |
Description
PA007759.h1Fs-b: Biotinylated Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Human IgG1 Fc Silent Kappa
Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
The recombinant SK3 / Anti-Leu 3a antibody binds to the human CD4 protein (cluster of differentiation 4), a glycoprotein and the co-receptor for the T-cell receptor (TCR). The CD4 protein is expressed on the surface of immune cells such as helper T cells, monocytes, macrophages, and dendritic cells.
References of Anti-Human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a)：
1. CD4+ T-cell subsets in inflammatory diseases: beyond the Th1/Th2 paradigm
Hirahara, K., et al. Int Immunol. 2016 Apr;28(4):163-71. PMID: 26969728
“The SK3 antibody (anti-human CD4, Leu 3a) was used in flow cytometry to identify CD4+ T-helper subsets in human peripheral blood mononuclear cells. SK3 staining enabled accurate gating of CD4+ cells, revealing distinct cytokine profiles in inflammatory conditions and highlighting novel therapeutic targets for autoimmune diseases.”
For more technical references or data sheets regarding the Anti-Human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a) formats, please contact our scientific support team at message@sydlabs.com.
Syd Labs provides the following in vivo grade recombinant anti-mouse CD4 monoclonal antibodies:
Recombinant Anti-mouse CD4 monoclonal antibody (Clone: GK1.5)
Recombinant Anti-mouse CD4 monoclonal antibody (Clone: YTS191)
Recombinant Anti-mouse CD4 monoclonal antibody (Clone: YTS 177.9.6.1)
Recombinant Anti-mouse CD4 monoclonal antibody (Clone: YTA 3.1.2)
Syd Labs provides the following in vivo grade recombinant anti-human CD4 monoclonal antibodies:
Recombinant Anti-human CD4 monoclonal antibody (Clone: SK3 / Anti-Leu 3a)
Recombinant Anti-human CD4 monoclonal antibody (Clone: OKT4)
Recombinant Anti-human CD4 monoclonal antibody (Clone: 13B8.2)
Recombinant Anti-human CD4 monoclonal antibody (Clone: OKT4A)
Clenoliximab biosimilar, research grade, anti-human CD4 monoclonal antibody
Ibalizumab biosimilar, research grade, anti-human CD4 monoclonal antibody
Syd Labs provides the following recombinant anti-mouse CD4 monoclonal antibodies for flow cytometry:
Recombinant Anti-mouse CD4 monoclonal antibody (Clone: GK1.5) for flow cytometry
Syd Labs provides the following recombinant anti-human CD4 monoclonal antibodies for flow cytometry:
Recombinant Anti-human CD4 monoclonal antibody (Clone: SK3 / Anti-Leu 3a) for flow cytometry
Recombinant Anti-human CD4 monoclonal antibody (Clone: OKT4) for flow cytometry
Recombinant Anti-human CD4 monoclonal antibody (Clone: 13B8.2) for flow cytometry
Recombinant Anti-human CD4 monoclonal antibody (Clone: OKT4A) for flow cytometry
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