Lorlatinib (PF-06463922)
Lorlatinib (PF-06463922) (CAS No.: 1454846-35-5) is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor. It has Kis of <0.025 nM, <0.07 nM, and 0.7 nM for ROS1, wild type ALK, and ALKL1196M, respectively. Its purity is...
AZD4547
Synonyms: ABSK091, AZD-4547, AZD 4547, ABSK 091, ABSK 091 AZD4547 is a potent selective inhibitor of the FGFR family with IC50 of 0.2nM, 2.5nM, and 1.8nM, respectively, for FGFR1, FGFR2, and FGFR3 in cell-free assays. AZD4547...
