Lorlatinib (PF-06463922)

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Lorlatinib (PF-06463922) (CAS No.: 1454846-35-5) is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor. It has Kis of <0.025 nM, <0.07 nM, and 0.7 nM for ROS1, wild type ALK, and ALKL1196M, respectively. Its purity is >99.5%.

Synonyms: ROS1 inhibitor, ALK inhibitor

For Research Use Only.

SKU: APIM050226
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