Vactosertib (CAS No.: 1352608-82-2), is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM.. >99% Purity. Synonyms: EW-7197, TEW-7197, EW7197, TEW7197, ALK5 inhibitor, ATP-competitive activin receptor-like kinase...
BLU-9931 (CAS No.: 1538604-68-0), a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 3 nM and a Kd of 6 nM. BLU-9931 has significant antitumor activity. >98%...
Nazartinib (EGF-816) (CAS No.: 1508250-71-2), a covalent mutant-selective EGFR inhibitor, with Ki and Kinact of 31 nM and 0.222 min-1 on EGFR(L858R/790M) mutant, respectively. >98% Purity. Synonyms: EGF-816, EGF816, EGFR inhibitor, epidermal growth factor receptor inhibitor For...
JNJ-4796 (CAS No.: 2241664-16-2), an oral active fusion inhibitor of influenza virus, neutralizing influenza A group 1 viruses by inhibiting hemagglutinin (HA)-mediated fusion. >98% Purity. Synonyms: JNJ4796, fusion inhibitor, influenza virus inhibitor For Research Use Only.
DEL-22379 (CAS No.: 181223-80-3), a potent and selective ERK Dimerization inhibitor. DEL-22379 inhibits ERK Dimerization without affecting ERK phosphorylation, forestalls tumorigenesis driven by RAS-ERK pathway oncogenes. Nearly 50% of human malignancies exhibit unregulated RAS-ERK...
BEC hydrochloride (CAS No.: 222638-67-7), a slow-binding and competitive Arginase II inhibitor. >98% Purity. Synonyms: BEC, BEC HCl, Arginase II inhibitor For Research Use Only.
RTA-408 (CAS No.: 1474034-05-3), a Novel Synthetic Triterpenoid That Binds to Kelch-like ECH-associated Protein 1 (Keap1) and Attenuate Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Degradation. >99% Purity. Synonyms: Omaveloxolone, Nuclear Factor Erythroid 2-Related Factor 2, Nrf2,...
ND-646 (CAS No.: 1434639-57-2), an Orally Bioavailable and Steric Inhibitor of Acetyl-CoA Carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for Recombinant hACC1 and hACC2, Respectively. >99% Purity. Synonyms: Acetyl-CoA Carboxylase, ACC For Research Use Only.
GSK-961081 (Batefenterol, TD-5959) (CAS No.: 743461-65-6), Novel Muscarinic Receptor Antagonist and β2
Etoposide Phosphate (BMY-40481) (CAS No.: 117091-64-2), potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands. Synonyms: topoisomerase II inhibitor, BMY-40481, BMY40481, BMY 40481 For Research Use Only.
