SLC12A1 / NKCC2 Rabbit mAb
$148.00 – $548.00
BSC; BSC1; CCC2; BSC-1; NKCC2
- Details & Specifications
- References
- More Offers
| Catalog No. | A20933 |
|---|---|
| Product Name | SLC12A1 / NKCC2 Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | BSC; BSC1; CCC2; BSC-1; NKCC2 |
| Gene Name | SLC12A1 |
| Protein Name | SLC12A1 |
| Uniprot/Swissprot ID | Q13621 |
| Gene ID | 6557 |
| Clone | ARC2915 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle’s loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.
No more offers for this product!
