PD-L1/CD274 Rabbit mAb

CD271 Unconjugated(111901) catalog number: 111901 Caprico Biotechnologies

PD-L1/CD274 Rabbit mAb

$218.00$358.00

In stock

$218.00$358.00

PD-L1/CD274 Rabbit mAb

Store
SKU: A20270
Clear
View cart
Catalog No. A20270
Product NamePD-L1/CD274 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms B7-H; B7H1; PDL1; PD-L1; hPD-L1; PDCD1L1; PDCD1LG1
Gene Name CD274
Protein Name CD274
Uniprot ID Q9NZQ7
Clonality Monoclonal
Source/Host Rabbit
Applications ELISA, WB, FC, Inhibition
Reactivity Human
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.

Additional information

Ship from Country

USA

Size

100 μL, 50 μL

No more offers for this product!