GSK046 (GSK-046, IBET-BD2)
GSK046 (iBET-BD2, GSK 046, GSK-046) (CAS No.: 2474876-09-8), a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4...
GSK923295
Synonyms: GSK-923295. GSK 923295 GSK923295 (GSK-923295) is a first-in-class high affinity antimitotic inhibitor of centromere-associated protein E (CENP-E), potently and allosterically inhibiting CENP-E ATPase activity (Ki = 3.2 nM) [1]. GSK923295 displays a broad-spectrum antiproliferative activity...