AFURESERTIB (GSK2110183)
$80.00 – $790.00
SKU: APIM050073 Categories: Chemicals, Inhibitors, Activators, Antagonists, and Agonists
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| Catalog No. | APIM050073 |
|---|---|
| Product Name | AFURESERTIB (GSK2110183) |
Description
Background Information:
Afuresertib (GSK2110183) is a cell-permeable, orally bioavailable, potent and selective ATP-competitive pan-AKT inhibitor with Ki at low nMs for all three iso-forms , currently in clinical evaluation for cancer treatment.
APIM050073: AFURESERTIB (GSK2110183)
CAS No.: 1047645-82-8 (HCl Salt) 1047644-62-1 (Free base).
Molecular Formula: C18H17Cl2FN4OS ? HCl.
Molecular Weight: 463.8.
Purity: 100% optical purity (chiral HPLC), >99.5% chemical purity (achiral HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO and Water.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
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