RMP1-14.1 antibody products
The RMP1-14.1 antibody, a highly specific anti mouse pd-1 monoclonal antibody targeting mouse PD-1 (CD279), delivers varied experimental outcomes depending on its isotype. For instance, the Recombinant RMP1-14.1 antibody (IgG2a) is the preferred choice for flow cytometry due to its high sensitivity, while the RMP1-14.1 antibody (IgG2c) excels in mouse models like C57BL/6 for in vivo studies. Researchers must select the appropriate isotype of this anti mouse cd279 antibody based on the experimental system, such as in vivo PD-1/PD-L1 pathway blockade or in vitro detection, to minimize cross-reactivity and ensure accurate results in cancer immunotherapy research.
The RMP1-14.1 antibody is renowned for its ability to effectively block the PD-1/PD-L1 pathway, making it a potent immune checkpoint inhibitor in immunological studies. The IgG2a version of the RMP1-14.1 antibody significantly boosts T-cell activity in melanoma mouse models, demonstrating its utility in cancer immunotherapy. This anti mouse pd 1 antibody is versatile, suitable for ELISA (with sensitivity <0.1 ng/mL), flow cytometry (including FITC-conjugated options), and in vivo therapeutic studies, offering researchers a reliable tool to investigate immune regulation and develop novel treatments.
When selecting the RMP1-14.1 antibody, key considerations include isotype-specific performance, with purity levels exceeding 98% and endotoxin levels below 1 EU/μg. The IgG2a RMP1-14.1 antibody is ideal for CD8+ T-cell co-culture assays, while the IgG2c isotype is better suited for pharmacodynamic studies in specific mouse models. Multi-isotype configuration kits for the RMP1-14.1 antibody allow researchers to optimize experimental conditions, reducing batch variability and enhancing reproducibility in studies focused on tumor immune evasion and cancer immunotherapy.
For detailed information about rmp-14.1 antibodies, please click: Anti-Mouse PD1 Monoclonal Antibodies Syd Labs.
We offer Anti-Mouse PD-1 Antibody (RMP1-14.1) related products：
PA007162.r2a: Recombinant Anti-mouse PD-1 Antibody (RMP1-14.1), Rat IgG2a Kappa
PA007162.m2cLA: Anti-mouse PD 1 Antibody (RMP1-14.1), Mouse IgG2c-L234A L235A P329G (LALAPG) Kappa
PA007162.m1DA: Anti-mouse PD-1 Monoclonal Antibody (Clone RMP1-14.1), Mouse IgG1-D265A Kappa
PA007162.m2a: Anti-mouse PD1 Monoclonal Antibody (Clone RMP1-14.1), Mouse IgG2a Kappa
PA007162.rt: Anti-mouse PD-1 Monoclonal Antibody (Clone RMP1-14.1), Rabbit IgG
PA007162.m2c: Anti-mouse PD 1 Antibody (Clone RMP1-14.1), Mouse IgG2c Kappa
PA007162.m1: Anti-mouse PD-1 Antibody (Clone RMP1-14.1), Mouse IgG1 Kappa
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Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
