Ataxin-3 (ATXN3) Rabbit mAb
$148.00 – $548.00
AT3; JOS; MJD; ATX3; MJD1; SCA3
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| Catalog No. | A22094 |
|---|---|
| Product Name | Ataxin-3 (ATXN3) Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | AT3; JOS; MJD; ATX3; MJD1; SCA3 |
| Gene Name | ATXN3 |
| Protein Name | ATXN3 |
| Uniprot/Swissprot ID | P54252 |
| Gene ID | 4287 |
| Clone | ARC54882 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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