Catalog No.	PA008006.m2a
Product Name	Anti-human CD3 / CD3 Bispecific Antibody (OKT3 / UCHT1) | PA008006.m2a
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	cluster of differentiation 3, CD3D, CD3E, CD3G
Clone	OKT3 / UCHT1.
Isotype	mouse IgG2a.
Applications	immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Form Of Antibody	0.2 μM filtered solution of 1x PBS.
Endotoxin	Less than 1 EU/mg of protein as determined by LAL method.
Purity	>95% by SDS-PAGE under reducing conditions.
Shipping	The in vivo grade recombinant mouse anti-human CD3 / CD3 bispecific antibodies are shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 3 month from date of receipt, 2 to 8°C as supplied. 12 months from date of receipt, -20°C to -70°C as supplied.
Note	Recombinant anti-human CD3 / CD3 bispecific antibodies share the variable region sequences with the mouse anti-human CD3 antibody (clone number: OKT3) and mouse anti-human CD3 antibody (clone number: UCHT1). The recombinant mouse IgG2a bispecific isotype control antibody available.
Order Offline	Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card.

Description

PA008006.m2a: In Vivo Grade Recombinant Anti-human CD3 / CD3 Bispecific Antibody, Mouse IgG2a Kappa (Clone OKT3 / UCHT1)

The in vivo grade recombinant mouse anti-human CD3 / CD3 bispecific antibody (mouse IgG2a kappa) was produced in mammalian cells.

Background

Our recombinant anti-human CD3 / CD3 (OKT3 / UCHT1) bispecific antibodies have a part (variable regions) or complete amino acid sequences of the mouse anti-human CD3 antibody (hybridoma clone name or number: OKT3 and UCHT1). It is under investigation how the recombinant anti-human CD3 / CD3 bispecific antibody behaves different from the individual monoclonal antibodies and their combination (OKT3 + UCHT1).

Recombinant anti-HEL / HEL Bispecific Isotype Control Antibodies:

In vivo Grade Recombinant anti-HEL / HEL Mouse IgG1 Kappa Bispecific Isotype Control Antibody
In vivo Grade Recombinant anti-HEL / HEL Mouse IgG2a Kappa Bispecific Isotype Control Antibody
In vivo Grade Recombinant anti-HEL / HEL Mouse IgG2c Kappa Bispecific Isotype Control Antibody

Syd Labs provides the following in vivo grade recombinant anti-human CD3 monoclonal antibodies:

Muromonab biosimilar, research grade, anti-human CD3 monoclonal antibody (Clone: OKT3)
Teplizumab biosimilar, research grade, anti-human CD3 monoclonal antibody (Clone: OKT3)
Foralumab biosimilar, research grade, anti-human CD3 monoclonal antibody (Clone: OKT3)
Recombinant Anti-human CD3 monoclonal antibody (Clone: OKT3)
Recombinant Anti-human CD3 monoclonal antibody (Clone: SP34-2)
Recombinant Anti-human CD3 monoclonal antibody (Clone: UCHT1)
Recombinant Anti-human CD3 monoclonal antibody (Clone: 12F6)
Recombinant Anti-human CD3 / CD3 Bispecific Antibody (Clone: OKT3 / UCHT1)
Recombinant Anti-human CD3 / CD3 Bispecific Antibody (Clone: OKT3 / SP34-2)
Recombinant Anti-human CD3 / CD3 Bispecific Antibody (Clone: SP34-2 / OKT3)

Syd Labs provides the following in vivo grade recombinant anti-mouse CD3 monoclonal antibodies:

Recombinant Anti-mouse CD3e monoclonal antibody (Clone: 145-2C11)
Recombinant Anti-mouse CD3e monoclonal antibody (Clone: 500A2)
Recombinant Anti-mouse CD3 monoclonal antibody (Clone: 17A2)

Syd Labs provides the following recombinant anti-mouse CD3 monoclonal antibodies for flow cytometry:

Recombinant Anti-mouse CD3 monoclonal antibody (Clone: 17A2) for flow cytometry
Recombinant Anti-mouse CD3e monoclonal antibody (Clone: 145-2C11) for flow cytometry
Recombinant Anti-mouse CD3e monoclonal antibody (Clone: 500A2) for flow cytometry

Syd Labs provides the following recombinant anti-human CD3 monoclonal antibodies for flow cytometry:

Recombinant Anti-human CD3 monoclonal antibody (Clone: OKT3) for flow cytometry
Recombinant Anti-human CD3 monoclonal antibody (Clone: UCHT1) for flow cytometry
Recombinant Anti-human CD3 monoclonal antibody (Clone: 12F6) for flow cytometry
Recombinant Anti-human CD3 monoclonal antibody (Clone: SP34-2) for flow cytometry

Questions and Answers about recombinant anti-human CD3 / CD3 bispecific antibody (Clone OKT3 / UCHT1):

Question: How did you design the anti-human CD3 / CD3 bispecific antibody?
Answer: Clones OKT3 and UCHT1 are the most well-known anti-human CD3 antibodies available in the market. These two clones both have extensive multi-year publication records supporting them. Their epitopes on the human CD3 protein overlap. Thus, the OKT3 / UCHT1 bispecific antibody may behave different from the individual or combined OKT3 and UCHT1 antibodies.

Question: Do you produce any recombinant Fc-silenced OKT3 / UCHT1 bispecific antibody?
Answer: We provide custom recombinant antibody production service to produce engineered versions of recombinant OKT3 / SP34-2 and SP34-2 / OKT3 bispecific antibodies, such as mIgG2c LALAPG, mIgG2a LALAPG, and mIgG1 D265A.

In Vivo Grade Recombinant Anti-human CD3 / CD3 Bispecific Antibody, Mouse IgG2a Kappa (Clone OKT3 / UCHT1) from: In Vivo Grade Recombinant Anti-human CD3 / CD3 Bispecific Antibody, Mouse IgG2a Kappa (Clone OKT3 / UCHT1): PA008006.m2a Syd Labs

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