Digoxin is a cardiac glycoside. Digoxin inhibits the sodium potassium adenosine triphosphatase (ATPase) pump, thereby increasing intracellular calcium and enhancing cardiac contractility. This agent also acts directly on the atrioventricular node to suppress conduction, thereby...
Abclonal CDKN2A/p16INK4a Mouse mAb (Catalog Number: A20371) generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related...
Abclonal Claudin18.2 Rabbit mAb (Catalog Number: A20420) encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands.
Abclonal MLH1 Mouse mAb (Catalog Number: A20544) encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system.
Abclonal Villin1 Mouse mAb (Catalog Number: A20545) encodes a member of a family of calcium-regulated actin-binding proteins.
In the mammalian genome, DNA methylation is an epigenetic mechanism involving the transfer of a methyl group onto the C5 position of the cytosine to form 5-methylcytosine. DNA methylation regulates gene expression by recruiting proteins...
