Custom lentivirus production services, lentivirus plasmid vector construction, helper-free lentivirus packaging, lentivirus purification by ultracentrifugation, filtration or chromatography, lentivirus titration by p24 ELISA, qPCR or HT1080 cell assay. High yield, high purity, high infectivity. Quality...
Custom AAV production services including AAV plasmid vector construction, helper-free AAV packaging, AAV purification by iodixanol density gradient ultracentrifugation or column chromatography, AAV titration by qPCR. Multiple serotypes. High yield, high purity, high infectivity. Quality...
We provide the services of developing stable cell lines for: G-Protein Coupled Receptors (GPCR) of high pharmacological relevance; other cell-based assays such as ion channel and kinases (RTKs).
Fast stable cell line generation service for antibody production: development of suspension CHO stable cell lines for antibody production. No virus involved. DNA Transfection and stable cell line screening only.
Kinetic analysis is used to determine the affinity of an antibody to its soluble antigen using surface plasmon resonance (SPR) or biolayer interferometry (BLI), which can measure kon, koff, and kD. Association and dissociation are...
A standard human Fcγ receptor panel binding assay in a high throughput format using the BLI platform. An FcRn binding assay to study pH-dependent interaction of antibody with the neonatal Fc-receptor (FcRn) in high throughput...
Capillary isoelectric focusing is an analytical technique for characterization of protein mixtures and determination of protein isoelectric points.
real-time PCR services (qPCR services, quantitative PCR services or qRT PCR services) for gene expression analysis and gene copy number determination includes RNA or DNA extraction, qPCR primer design and validation, qPCR reaction optimization, and...
Extensive experience with making DNA constructs for small peptide tag (such as FLAG tag, His tag, HA tag, and myc tag) fusion protein production, expressing and purifying a number of FLAG tag, His tag, HA...
to obtain the intact amino acid sequence of variable and/or constant regions of monoclonal antibodies by LC-MS/MS.
