Mineralocorticoid receptor (NR3C2) Rabbit mAb
$148.00 – $548.00
MR; MCR; MLR; NR3C2VIT
- Details & Specifications
- References
- More Offers
| Catalog No. | A21058 |
|---|---|
| Product Name | Mineralocorticoid receptor (NR3C2) Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | MR; MCR; MLR; NR3C2VIT |
| Gene Name | NR3C2 |
| Protein Name | NR3C2 |
| Uniprot/Swissprot ID | P08235 |
| Gene ID | 4306 |
| Clone | ARC51728 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
No more offers for this product!
