Catalog No.	A19082
Product Name	[KO Validated] MyD88 Rabbit mAb
Supplier Name	ABclonal, Inc.
Brand Name	Abclonal
Synonyms	WM1; IMD68; MYD88D
Gene Name	MYD88
Protein Name	MYD88
Uniprot/Swissprot ID	Q99836
Gene ID	4615
Clone	ARC52507
Clonality	Monoclonal
Source/Host	Rabbit
Reactivity	Human, Mouse, Rat
Conjugate	Unconjugated
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

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