CD40 Rabbit mAb

CD271 Unconjugated(111901) catalog number: 111901 Caprico Biotechnologies

CD40 Rabbit mAb

$218.00$358.00

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$218.00$358.00

CD40 Rabbit mAb

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SKU: A20214
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Catalog No. A20214
Product NameCD40 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms p50; Bp50; CDW40; TNFRSF5
Gene Name CD40
Protein Name CD40
Uniprot ID P25942
Clonality Monoclonal
Source/Host Rabbit
Applications FC
Reactivity Human
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Additional information

Ship from Country

USA

Size

100 μL, 50 μL

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