AZD4573 (AZD-4573)
$160.00 – $750.00
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| Catalog No. | APIM050098 |
|---|---|
| Product Name | AZD4573 (AZD-4573) |
Description
Background Information:
AZD4573 is a potent inhibitor of CDK9 with a biochemical IC50 of 10 fold) against all other CDKs and kinases. AZD4573 rapidly induces cell death in hematological tumor models (both in vitro and in vivo) through depletion of Mcl-1 (ref. 1).
Reference:
1. J. Cidado, et al, AZD4573, a novel CDK9 inhibitor, rapidly induces cell death in hematological tumor models through depletion of Mcl1 [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl): Abstract nr 310.
APIM050016: AZD4573
CAS No.: 2057509-72-3.
Molecular Formula: C22H28ClN5O2.
Molecular Weight: 429.9.
Purity: >99.5% Pure by Achiral and Chiral HPLCs.
QC: Achiral and Chiral HPLCs, MS, NMR, and Quantitative Elemental analysis Report.
Solubility: Refer to Certificate of Analysis.
Storage: Refer to Certificate of Analysis.