We can optimize stable and transient expression for secreted or intracellular, cytosolic or periplasmic, tagged or untagged proteins. We assess expression levels using the methods of SDS-PAGE, Western, ELISA or functional analysis.
developed human monoclonal antibodies and monkey monoclonal antibodies using antigen specific single B cell-based antibody generation technologies. After detection and isolation of antigen specific memory B cells by flow cytometry-based single B cell sorting, the...
Antibody humanization service using empirical and rational approaches. Humanized antibodies are designed by our proprietary humanization and optimization algorithm, and made by gene synthesis and fusion with human antibody backbones.
single B cell antibody discovery technologies for antigen specific single B cell antibody sequencing after flow cytometry-based single B cell sorting. rabbit memory B cell culture, mouse plasma cell antibody cloning.
Celetrix cell electroporation large-scale model SLT (catalog No. 11-0104) is a unique CHO electroporation machine for large scale protein transient production in CHO cells. The largest scale (10 ml electroporation tube): 2x10E9 CHO cells per...
Celetrix PBMC cell electroporation upgrade model EX+ (11-0106) is an upgraded version of model LE+ (11-0101) with larger electroporation volume (600 ul and 1 ml electroporation tubes) and the option of the electrofusion function for...
Celetrix T cell electroporation upgrade model LE+ (11-0101) can be used to transfect a variety of mammalian cell line, especially PBMC, with high-efficiency and low-toxicity electroporation. It can maintain a high level of T cell...
Lorlatinib (PF-06463922) (CAS No.: 1454846-35-5) is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor. It has Kis of <0.025 nM, <0.07 nM, and 0.7 nM for ROS1, wild type ALK, and ALKL1196M, respectively. Its purity is...
