Search Results - SW

BI-3406

BI-3406 (CAS No.: 2230836-55-0), a highly potent, selective, and orally bioavailable inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM. Synonyms: KRAS and Son of Sevenless 1...

ALTIRATINIB (DCC-2701)

Background Information: Abstract (Ref 1): Altiratinib (DCC-2701) was designed based on the rationale of engineering a single therapeutic agent able to address multiple hallmarks of cancer. Specifically, Altiratinib inhibits not only mechanisms of tumor initiation and...