Search Results - 25

RTA-408 (Omaveloxolone)

RTA-408 (CAS No.: 1474034-05-3), a Novel Synthetic Triterpenoid That Binds to Kelch-like ECH-associated Protein 1 (Keap1) and Attenuate Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Degradation. >99% Purity. Synonyms: Omaveloxolone, Nuclear Factor Erythroid 2-Related Factor 2, Nrf2,...

ND-646

ND-646 (CAS No.: 1434639-57-2), an Orally Bioavailable and Steric Inhibitor of Acetyl-CoA Carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for Recombinant hACC1 and hACC2, Respectively. >99% Purity. Synonyms: Acetyl-CoA Carboxylase, ACC For Research Use Only.

Etoposide phosphate (BMY-40481)

Etoposide Phosphate (BMY-40481) (CAS No.: 117091-64-2), potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands. Synonyms: topoisomerase II inhibitor, BMY-40481, BMY40481, BMY 40481 For Research Use Only.

Glumetinib (SCC244)

Glumetinib (SCC244) is a highly selective, orally bioavailable, ATP-competitive c-Met inhibitor with an IC50 of 0.42 nM. Glumetinib has greater than 2400-fold selectivity for c-Met over those 312 kinases evaluated, including the c-Met family member...

KB-0742 dihydrochloride (KB0742)

KB0742 (KB-0742, KB 0742) (CAS No.: 2416874-75-2), an orally bioavailable, potent and selective CDK9 inhibitor with an IC50 of 6 nM, highly selective against other CDKs (>60 fold). 99% Chem and Optical Purity. Synonyms: KB-0742, KB 0742,...

BI-3406

BI-3406 (CAS No.: 2230836-55-0), a highly potent, selective, and orally bioavailable inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM. Synonyms: KRAS and Son of Sevenless 1...