Catalog No.	A22724
Product Name	[KO Validated] TRIM21/SS-A Rabbit mAb
Supplier Name	ABclonal, Inc.
Brand Name	Abclonal
Synonyms	SSA; RO52; SSA1; RNF81; Ro/SSA
Gene Name	TRIM21
Protein Name	TRIM21
Uniprot/Swissprot ID	P19474
Gene ID	6737
Clone	ARC57363
Clonality	Monoclonal
Source/Host	Rabbit
Reactivity	Human
Conjugate	Unconjugated
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

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