Abclonal SATB2 Rabbit mAb (Catalog Number: A20220) encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling.
Abclonal β-Catenin Mouse mAb (Catalog Number: A20221) encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers...
Abclonal CD31/PECAM1 Rabbit mAb (Catalog Number: A20228) encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular...
Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling...
Digoxin is a cardiac glycoside. Digoxin inhibits the sodium potassium adenosine triphosphatase (ATPase) pump, thereby increasing intracellular calcium and enhancing cardiac contractility. This agent also acts directly on the atrioventricular node to suppress conduction, thereby...
Abclonal CDKN2A/p16INK4a Mouse mAb (Catalog Number: A20371) generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related...
Abclonal Claudin18.2 Rabbit mAb (Catalog Number: A20420) encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands.
Abclonal MLH1 Mouse mAb (Catalog Number: A20544) encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system.
