PRT-060318 (PRT318, P142–76)

PRT-060318 (PRT318, P142–76) (CAS No.: 1194961-19-7), a potent and selective inhibitor of spleen tyrosine kinase (Syk; IC₅₀ = 4 nM). It is selective, inhibiting 92% of Syk activity, while other kinases retain >70% activity, at a concentration of 50 nM in a panel of 270 kinases. >98% Purity.

Synonyms: PRT060318, PRT318, P142–76, PRT-318, Syk inhibitor, spleen tyrosine kinase inhibitor

For Research Use Only.