Human TNFR2/CD120b/TNFRSF1B Protein (TNF-HM2R2)
$216.00 – $720.00
KACTUS Biosystems Human TNFR2/CD120b/TNFRSF1B Protein (TNF-HM2R2) (catalog No. TNF-HM2R2) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu23-Asp257.
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| Catalog No. | TNF-HM2R2 |
|---|---|
| Product Name | Human TNFR2/CD120b/TNFRSF1B Protein (TNF-HM2R2) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | P20333-1 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Leu23-Asp257 |
| Molecular Weight | The protein has a predicted MW of 51.89 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
TNF-HM2R2: Human TNFR2/CD120b/TNFRSF1B Protein (TNF-HM2R2)
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Please remember our product information: Human TNFR2/CD120b/TNFRSF1B Protein (TNF-HM2R2) catalog number: TNF-HM2R2 KACTUS Biosystems