Human LILRB1/CD85j/ILT2 Protein (LIL-HM3B1)
$243.00 – $810.00
KACTUS Biosystems Human LILRB1/CD85j/ILT2 Protein (LIL-HM3B1) (catalog No. LIL-HM3B1) is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Gly24-His458.
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| Catalog No. | LIL-HM3B1 |
|---|---|
| Product Name | Human LILRB1/CD85j/ILT2 Protein (LIL-HM3B1) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | ILT2; ILT-2; ILT2FLJ37515; LILRB1; LIR1; MIR7; CD85J; XXbac-BCX85G21.4 |
| Species | Human |
| Source | HEK293 |
| Accession | Q8NHL6-1 |
| Product Tag | C-mFc |
| Biotinylated | no |
| Exact Sequence | Gly24-His458 |
| Molecular Weight | The protein has a predicted MW of 73.5 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
LIL-HM3B1: Human LILRB1/CD85j/ILT2 Protein (LIL-HM3B1)
LILRB1, also known as CD85j and ILT2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response.
Please remember our product information: Human LILRB1/CD85j/ILT2 Protein (LIL-HM3B1) catalog number: LIL-HM3B1 KACTUS Biosystems