Human LAIR1/CD305 Protein (LAI-HM2R1)
$283.50 – $945.00
KACTUS Biosystems Human LAIR1/CD305 Protein (LAI-HM2R1) (catalog No. LAI-HM2R1) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-His163.
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| Catalog No. | LAI-HM2R1 |
|---|---|
| Product Name | Human LAIR1/CD305 Protein (LAI-HM2R1) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CD305; HLAIR1; LAIR1; LAIR-1 |
| Species | Human |
| Source | HEK293 |
| Accession | Q6GTX8-1 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Gln22-His163 |
| Molecular Weight | The protein has a predicted MW of 42.4 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
LAI-HM2R1: Human LAIR1/CD305 Protein (LAI-HM2R1)
LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation.
Please remember our product information: Human LAIR1/CD305 Protein (LAI-HM2R1) catalog number: LAI-HM2R1 KACTUS Biosystems