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Human FcRn Protein (FRN-HM101)
$290.70 – $967.50
KACTUS Biosystems Human FcRn Protein (FRN-HM101) (catalog No. FRN-HM101) is expressed from HEK293 with His tag at the C-Terminus.It contains Ala24-Ser297(FCGRT) & Ile21-Met119(B2M).
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| Catalog No. | FRN-HM101 |
|---|---|
| Product Name | Human FcRn Protein (FRN-HM101) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | FcRn alpha chain; FCGRT; FCRN; FCGRT&B2M |
| Species | Human |
| Source | HEK293 |
| Accession | P55899-1(FCGRT)&P61769-1(B2M) |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Ala24-Ser297(FCGRT) & Ile21-Met119(B2M) |
| Molecular Weight | The protein has a predicted MW of 31.5 kDa (FCGRT) & 11.7 kDa (B2M). Due to glycosylation, the protein migrates to 35-40 kDa (FCGRT) & 13-14 kDa (B2M) based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
FRN-HM101: Human FcRn Protein (FRN-HM101)
The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.
Please remember our product information: Human FcRn Protein (FRN-HM101) catalog number: FRN-HM101 KACTUS Biosystems
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