Human FAM3D Protein (FAM-HM23D)
$270.00 – $900.00
KACTUS Biosystems Human FAM3D Protein (FAM-HM23D) (catalog No. FAM-HM23D) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Tyr26-Phe224.
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| Catalog No. | FAM-HM23D |
|---|---|
| Product Name | Human FAM3D Protein (FAM-HM23D) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | EF7; FAM3D; OIT1 |
| Species | Human |
| Source | HEK293 |
| Accession | Q96BQ1 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Tyr26-Phe224 |
| Molecular Weight | The protein has a predicted MW of 48.7 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
FAM-HM23D: Human FAM3D Protein (FAM-HM23D)
The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity to chemically induced colitis associated with high incidence of cancer.
Please remember our product information: Human FAM3D Protein (FAM-HM23D) catalog number: FAM-HM23D KACTUS Biosystems