Human c-MPL/Thrombopoietin R Protein (MPL-HM101)
$310.50 – $1,035.00
KACTUS Biosystems Human c-MPL/Thrombopoietin R Protein (MPL-HM101) (catalog No. MPL-HM101) is expressed from HEK293 with His tag at the C-Terminus.It contains Gln26-Trp491.
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| Catalog No. | MPL-HM101 |
|---|---|
| Product Name | Human c-MPL/Thrombopoietin R Protein (MPL-HM101) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | TPO-R; CD110; MPL; c-Mpl; MPLV; K12 |
| Species | Human |
| Source | HEK293 |
| Accession | P40238-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Gln26-Trp491 |
| Molecular Weight | The protein has a predicted MW of 53.6 kDa. Due to glycosylation, the protein migrates to 68-70 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
MPL-HM101: Human c-MPL/Thrombopoietin R Protein (MPL-HM101)
The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML.
Please remember our product information: Human c-MPL/Thrombopoietin R Protein (MPL-HM101) catalog number: MPL-HM101 KACTUS Biosystems
