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Human Beta Klotho Protein (KLB-HM101)
$945.00 – $3,150.00
KACTUS Biosystems Human Beta Klotho Protein (KLB-HM101) (catalog No. KLB-HM101) is expressed from HEK293 with His tag at the C-Terminus.It contains Met30-Thr983.
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| Catalog No. | KLB-HM101 |
|---|---|
| Product Name | Human Beta Klotho Protein (KLB-HM101) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | betaKlotho; beta-klotho; BKL; KLB; klotho beta like; Klotho beta; MGC142213 |
| Species | Human |
| Source | HEK293 |
| Accession | Q86Z14 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Met30-Thr983 |
| Molecular Weight | The protein has a predicted MW of 111.6 kDa. Due to glycosylation, the protein migrates to 115-130 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
KLB-HM101: Human Beta Klotho Protein (KLB-HM101)
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites.
Please remember our product information: Human Beta Klotho Protein (KLB-HM101) catalog number: KLB-HM101 KACTUS Biosystems
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