ALAS1 Rabbit mAb
$148.00 – $548.00
ALAS; MIG4; ALAS3; ALASH; ALAS-H
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| Catalog No. | A4817 | 
|---|---|
| Product Name | ALAS1 Rabbit mAb | 
| Supplier Name | ABclonal, Inc. | 
| Brand Name | Abclonal | 
| Synonyms | ALAS; MIG4; ALAS3; ALASH; ALAS-H | 
| Gene Name | ALAS1 | 
| Protein Name | ALAS1 | 
| Uniprot/Swissprot ID | P13196 | 
| Gene ID | 211 | 
| Clone | ARC0239 | 
| Clonality | Monoclonal | 
| Source/Host | Rabbit | 
| Reactivity | Human | 
| Conjugate | Unconjugated | 
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. | 
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com | 
Description
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
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