2′-O-Methylguanosine(Gm) Rabbit mAb
$148.00 – $548.00
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| Catalog No. | A20696 |
|---|---|
| Product Name | 2′-O-Methylguanosine(Gm) Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Clone | ARC50772 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Species independent |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2′-O-methyladenosine (Am), 2′-O-methylguanosine (Gm),2′-O-methylcytidine (Cm),2′-O-methyluridine (Um),N 6-methyladenosine (m6A), N 1-methylguanosine (m1G),5-methylcytidine (m5C),and 5-methyluridine (m5U) are representative 2′-O-methylation and base-methylation modified epigenetic marks of RNA. 2′-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2′-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2′-O-methylguanosine is thought to stabilize the structure of the tRNA.
