Etanercept Biosimilar | C075P

Catalog No.	C075P
Product Name	Etanercept Biosimilar | C075P
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	TNF Inhibitor, Tumor Necrosis Factor Alpha Inhibitor
Source/Host	The etanercept biosimilar protein was produced in the Enbrel biosimilar CHO stable cell line.
Specificity/Sensitivity	The etanercept biosimilar protein specifically binds to the human TNF alpha.
Form Of Antibody	0.2 uM filtered solution, pH 7.1 to 7.7, no stabilizers or preservatives.
Endotoxin	<1 EU/mg of the protein by the LAL method.
Purity	>95% by SDS-PAGE under reducing conditions and HPLC.
Shipping	The research grade etanercept biosimilar protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
Note	The research grade etanercept biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls and recombinant hIgG1 Fc proteins are available.
Order Offline	Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card.

Description

C075P: Etanercept Biosimilar

Background

What is research grade Etanercept biosimilar? Research grade Etanercept biosimilar has the same amino acid sequence as Etanercept (trade name Enbrel), a fusion protein of the soluble TNF receptor 2 and a Fc fragment (human IgG1 isotype). Etanercept can be used to treat autoimmune diseases by interfering with tumor necrosis factor (TNF), a soluble inflammatory cytokine, by acting as a TNF inhibitor. TNF alpha is the “master regulator” of the inflammatory (immune) response in many organ systems. Autoimmune diseases are caused by an overactive immune response. Etanercept has the potential to treat these diseases by inhibiting TNF alpha. Etanercept binds to TNF alpha and decreases its role in disorders involving excess inflammation in humans and other animals, including autoimmune diseases such as ankylosing spondylitis, juvenile rheumatoid arthritis, psoriasis, psoriatic arthritis, rheumatoid arthritis, and, potentially, in a variety of other disorders mediated by excess TNF alpha.

Syd Labs provides the following research grade anti-TNF alpha antibody biosimilars:
Infliximab biosimilar, research grade, anti-human TNF alpha monoclonal antibody
Adalimumab biosimilar, research grade, anti-human TNF alpha monoclonal antibody

Please remember our product information: Etanercept Biosimilar: C075P Syd Labs

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