PLC gamma 2 (PLCG2) Rabbit mAb
$148.00 – $548.00
FCAS3; APLAID; PLC-IV; PLC-gamma-2
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| Catalog No. | A5182 |
|---|---|
| Product Name | PLC gamma 2 (PLCG2) Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | FCAS3; APLAID; PLC-IV; PLC-gamma-2 |
| Gene Name | PLCG2 |
| Protein Name | PLCG2 |
| Uniprot/Swissprot ID | P16885 |
| Gene ID | 5336 |
| Clone | ARC1176 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
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