Catalog No.	APIM050179
Product Name	LDK378 (CERITINIB)

Description

Background Information:

LDK378(Ceritinib) is a highly selective, orally bioavailable and
ATP-competitive small molecule inhibitor of ALK (Anaplastic Lymphoma
Kinase), a receptor tyrosine kinase considered to be an important lung
cancer drug target. LDK378 displays enhanced potency over Crizotinib and
noteworthy antitumor activity for ALK-activated, non-small cell lung
cancer (NSCLC).

APIM050179: LDK378 (CERITINIB)

CAS No.: 1032900-25-6.
Molecular Formula: C₂₈H₃₆ClN₅O₃S.
Molecular Weight: 558.1.
Purity: >99% (by HPLC at 214 and 254 nm).
QC: HPLC-MS, ¹HNMR, and Quantitative Elemental Analysis.
Solubility: Refer to Certificate of Analysis.
Storage: Refer to Certificate of Analysis.

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