Catalog No.	A20986
Product Name	[KD Validated] Calreticulin Rabbit mAb
Supplier Name	ABclonal, Inc.
Brand Name	Abclonal
Synonyms	RO; CRT; SSA; cC1qR; HEL-S-99n
Gene Name	CALR
Protein Name	CALR
Uniprot/Swissprot ID	P27797
Gene ID	811
Clone	ARC51269
Clonality	Monoclonal
Source/Host	Rabbit
Reactivity	Human, Mouse, Rat
Conjugate	Unconjugated
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.

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