Catalog No.	C058P
Product Name	Ibalizumab Biosimilar, Human CD4 Antibody | C058P
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	TMB-355, TNX-355, Ibalizumab-uiyk
Summary	The monoclonal antibody ibalizumab biosimilar was produced in mammalian cells.
Isotype	Human IgG4 kappa.
Specificity/Sensitivity	The monoclonal antibody ibalizumab biosimilar specifically binds to the human CD4 protein.
Applications	ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by ibalizumab.
Form Of Antibody	0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin	<1 EU/mg of the protein by the LAL method.
Purity	>95% by SDS-PAGE under reducing conditions and HPLC.
Shipping	The monoclonal antibody ibalizumab is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, 2 to 8°C as supplied.
Note	The research grade ibalizumab biosimilar protein is for research use only (RUO). Recombinant human IgG4 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Order Offline	Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card.

Description

C058P: Ibalizumab Biosimilar, Human CD4 Monoclonal Antibody

Recombinant Humanized IgG4 Monoclonal Antibody.

Background

What is ibalizumab biosimilar research grade? Ibalizumab Biosimilar uses the same protein sequences as the therapeutic antibody ibalizumab which is a non-immunosuppressive humanised monoclonal antibody that binds CD4, the primary receptor for HIV, and inhibits HIV from entering cells. It is a post-attachment inhibitor, blocking HIV from binding to the CCR5 and CXCR4 co-receptors after HIV binds to the CD4 receptor on the surface of a CD4 cell. Post-attachment inhibitors are a subclass of HIV drugs called entry inhibitors.

Recombinant anti-HIV CD4-Binding Site Monoclonal Antibodies:
Recombinant Anti-HIV CD4-Binding Site Monoclonal Antibody (Clone N6), In Vivo Grade
Recombinant Anti-HIV CD4-Binding Site Monoclonal Antibody (Clone VRC07-523LS), In Vivo Grade
Recombinant Anti-HIV CD4-Binding Site Monoclonal Antibody (Clone 3BNC117), In Vivo Grade
Recombinant Anti-HIV CD4-Binding Site Monoclonal Antibody (Clone VRC01), In Vivo Grade

Other Recombinant anti-HIV Monoclonal Antibodies:
Recombinant Anti-HIV V3 Loop Glycan Monoclonal Antibody (Clone 10-1074), In Vivo Grade
Recombinant Anti-HIV V3 Loop Glycan Monoclonal Antibody (Clone PGT121), In Vivo Grade
Recombinant Anti-HIV gp120-gp41 Interface Monoclonal Antibody (Clone PGT151), In Vivo Grade
Recombinant Anti-HIV gp120-gp41 Interface Monoclonal Antibody (Clone 35O22), In Vivo Grade
Recombinant Anti-HIV gp120-gp41 Interface Monoclonal Antibody (Clone PGT152), In Vivo Grade
Recombinant Anti-HIV V1V2 Loop Glycan Monoclonal Antibody (Clone PGDM1400), In Vivo Grade
Recombinant Anti-HIV V1V2 Loop Glycan Monoclonal Antibody (Clone PG9), In Vivo Grade
Recombinant Anti-HIV V1V2 Loop Glycan Monoclonal Antibody (Clone CAP256-VRC26.25), In Vivo Grade
Recombinant Anti-HIV V2 Apex Monoclonal Antibody (Clone VRC38.01), In Vivo Grade
Recombinant Anti-HIV V2 Apex Monoclonal Antibody (Clone PGT145), In Vivo Grade
Recombinant Anti-HIV GP120 Outer Domain Monoclonal Antibody (Clone PGT128), In Vivo Grade
Recombinant Anti-HIV GP120 Outer Domain Monoclonal Antibody (Clone 2G12), In Vivo Grade
Recombinant Anti-HIV GP120 Outer Domain Monoclonal Antibody (Clone VRC13.01), In Vivo Grade

Ibalizumab Biosimilar from: Ibalizumab Biosimilar, Human CD4 Monoclonal Antibody: C058P Syd Labs

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