Matuzumab Biosimilar, Anti-human EGFR Monoclonal Antibody
$250.00 – $2,500.00
Matuzumab Biosimilar, EGFR Monoclonal Antibody. The research grade Matuzumab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
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| Catalog No. | C051P |
|---|---|
| Product Name | Matuzumab Biosimilar, Anti-human EGFR Monoclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | epidermal growth factor receptor, EGF receptor |
| Summary | Recombinant Humanized IgG1 Monoclonal Antibody. |
| Source/Host | The anti-human EGFR monoclonal antibody matuzumab biosimilar was produced in mammalian cells. |
| Specificity/Sensitivity | The research grade matuzumab biosimilar specifically binds to the human epidermal growth factor receptor (EGFR). |
| Applications | ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by matuzumab. |
| Form Of Antibody | 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives. |
| Endotoxin | < 1 EU per 1 mg of the protein by the LAL method. |
| Purity | >95% by SDS-PAGE under reducing conditions and HPLC. |
| Shipping | The research grade matuzumab biosimilar is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| Note | The research grade Matuzumab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card. |
Description
C051P: Matuzumab Biosimilar, EGFR Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Background
Matuzumab Biosimilar uses the same protein sequences as the therapeutic antibody matuzumab.
Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR (epithelial growth factor receptor), frequently associated with the growth of blood vessels in malignancy, facilitating tumor growth and survival.
Matuzumab binds the epidermal growth factor receptor (EGFR) with high affinity, competitively blocking natural ligand binding and blocking receptor-mediated downstream signalling, resulting in impaired tumor cell proliferation. Matuzumab (EMD-72000) is a humanized IgG1 MAb that not only binds with high specificity and affinity to EGFR, but also modulates antibody-dependent cellular cytotoxicity (ADCC).
Please remember our product information: Matuzumab Biosimilar, EGFR Monoclonal Antibody: C051P Syd Labs
Additional information
| Size | 1 mg, 20 mg, 5 mg |
|---|