Human MDL-1/CLEC5A Protein (CLE-HM25A)
$270.00 – $900.00
KACTUS Biosystems Human MDL-1/CLEC5A Protein (CLE-HM25A) (catalog No. CLE-HM25A) is expressed from HEK293 with hFc tag at the N-Terminus.It contains Tyr26-Lys188.
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| Catalog No. | CLE-HM25A |
|---|---|
| Product Name | Human MDL-1/CLEC5A Protein (CLE-HM25A) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | MDL-1; CLECSF5; MDL1; CLEC5A; DAP12-associating lectin 1 |
| Species | Human |
| Source | HEK293 |
| Accession | Q9NY25-1 |
| Product Tag | N-hFc |
| Biotinylated | no |
| Exact Sequence | Tyr26-Lys188 |
| Molecular Weight | The protein has a predicted MW of 46 kDa. Due to glycosylation, the protein migrates to 63-70 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
CLE-HM25A: Human MDL-1/CLEC5A Protein (CLE-HM25A)
In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.
Please remember our product information: Human MDL-1/CLEC5A Protein (CLE-HM25A) catalog number: CLE-HM25A KACTUS Biosystems
