Human FGFR4 Protein (FGF-HM2R4)
$135.00 – $450.00
KACTUS Biosystems Human FGFR4 Protein (FGF-HM2R4) (catalog No. FGF-HM2R4) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu22-Asp369.
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Catalog No. | FGF-HM2R4 |
---|---|
Product Name | Human FGFR4 Protein (FGF-HM2R4) |
Supplier Name | KACTUS Biosystems |
Brand Name | KACTUS Biosystems |
Synonyms | CD334; FGF R4; FGFR4; FGFR-4; MGC20292; JTK2; TKF |
Species | Human |
Source | HEK293 |
Accession | P22455 |
Product Tag | C-hFc |
Biotinylated | no |
Exact Sequence | Leu22-Asp369 |
Molecular Weight | The protein has a predicted MW of 65.3 kDa. Due to glycosylation, the protein migrates to 80-95 kDa based on Tris-Bis PAGE result. |
Form | Lyophilized |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per μg by the LAL method. |
Shipping | Shipped at ambient temperature. |
Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
FGF-HM2R4: Human FGFR4 Protein (FGF-HM2R4)
Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19.
Please remember our product information: Human FGFR4 Protein (FGF-HM2R4) catalog number: FGF-HM2R4 KACTUS Biosystems