Human CDH17/Cadherin 17 Domain 7 Protein (CDH-HM2D3)
$351.00 – $1,170.00
KACTUS Biosystems Human CDH17/Cadherin 17 Domain 7 Protein (CDH-HM2D3) (catalog No. CDH-HM2D3) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala668-Gly777.
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Catalog No. | CDH-HM2D3 |
---|---|
Product Name | Human CDH17/Cadherin 17 Domain 7 Protein (CDH-HM2D3) |
Supplier Name | KACTUS Biosystems |
Brand Name | KACTUS Biosystems |
Species | Human |
Source | HEK293 |
Accession | Q12864 |
Product Tag | C-hFc |
Biotinylated | no |
Exact Sequence | Ala668-Gly777 |
Molecular Weight | The protein has a predicted MW of 38.42 kDa. Due to glycosylation, the protein migrates to 48-52 kDa based on Tris-Bis PAGE result. |
Form | Liquid |
Formulation | Supplied as 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). |
Purity | > 95% as determined by Tris-Bis PAGE |
Endotoxin | Less than 1EU per μg by the LAL method. |
Shipping | Shipped with dry ice. |
Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
CDH-HM2D3: Human CDH17/Cadherin 17 Domain 7 Protein (CDH-HM2D3)
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Please remember our product information: Human CDH17/Cadherin 17 Domain 7 Protein (CDH-HM2D3) catalog number: CDH-HM2D3 KACTUS Biosystems