Biotinylated Human TLR3 Protein (Primary Amine Labeling) (TLR-HM103B)
$472.50 – $1,575.00
KACTUS Biosystems Biotinylated Human TLR3 Protein (Primary Amine Labeling) (TLR-HM103B) (catalog No. TLR-HM103B) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser23-Glu703.
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| Catalog No. | TLR-HM103B |
|---|---|
| Product Name | Biotinylated Human TLR3 Protein (Primary Amine Labeling) (TLR-HM103B) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | TLR3; CD283; IIAE2 |
| Species | Human |
| Source | HEK293 |
| Accession | Q6PCD4 |
| Product Tag | C-His |
| Biotinylated | yes |
| Exact Sequence | Ser23-Glu703 |
| Molecular Weight | The protein has a predicted MW of 78.7 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
TLR-HM103B: Biotinylated Human TLR3 Protein (Primary Amine Labeling) (TLR-HM103B)
TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to provide resistance to other pathogens in TLR3-deficient patients. Human TLR3 appears to be redundant in host defense to most microbes but is vital for natural immunity to HSV-1 in the CNS, which suggests that neurotropic viruses have contributed to the evolutionary maintenance of TLR3.
Please remember our product information: Biotinylated Human TLR3 Protein (Primary Amine Labeling) (TLR-HM103B) catalog number: TLR-HM103B KACTUS Biosystems
