Anti-mouse PD-1 / VEGFR-2 Bispecific Antibody (Clone:RMP1-14.1/DC101) | PA008026.m2cLA
$595.00 – $1,750.00
Recombinant anti-mouse PD-1 / VEGFR-2 bispecific antibodies share the variable region sequences with the rat anti-mouse PD-1 antibody (clone number: RMP1-14) and the rat anti-mouse VEGFR-2 antibody (clone number: DC101). The recombinant mouse IgG2c LALAPG bispecific isotype control antibody available.
- Details & Specifications
- References
| Catalog No. | PA008026.m2cLA |
|---|---|
| Product Name | In Vivo Grade Recombinant Anti-mouse PD-1 / VEGFR-2 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone RMP1-14.1 / DC101) |
| Data Sheet | 📄 Download Product Data Sheet (PDF) |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | PD-1 / VEGFR2 Bispecific, PD1 / VEGFR-2 Bispecific, VEGFR-2 / PD-1 Bispecific, VEGFR2 / PD-1 Bispecific |
| Clone | RMP1-14.1, the same variable region sequences as the rat anti-mouse PD-1 monoclonal antibody (clone number: RMP1-14). DC101, the same variable region sequences as the rat anti-mouse VEGFR-2 monoclonal antibody (clone number: DC101). |
| Isotype | Mouse IgG2c-LALAPG，Kappa |
| Applications | immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays. |
| Form Of Antibody | 0.2 μM filtered solution of 1x PBS. |
| Endotoxin | Less than 1 EU/mg of protein as determined by LAL method. |
| Purity | >95% by SDS-PAGE under reducing conditions. |
| Shipping | The in vivo grade recombinant rat anti-mouse PD-1 / VEGFR-2 bispecific antibodies are shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 3 month from date of receipt, 2 to 8°C as supplied. 12 months from date of receipt, -20°C to -70°C as supplied. |
| Note | Recombinant anti-mouse PD-1 / VEGFR-2 bispecific antibodies share the variable region sequences with the rat anti-mouse PD-1 antibody (clone number: RMP1-14) and the rat anti-mouse VEGFR-2 antibody (clone number: DC101). The recombinant mouse IgG2c LALAPG bispecific isotype control antibody available. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card. |
Description
PA008026.m2cLA: In Vivo Grade Recombinant Anti-mouse PD-1 / VEGFR-2 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone RMP1-14.1 / DC101)
The in vivo grade recombinant anti-mouse PD-1 / VEGFR-2 bispecific antibody (mouse IgG2c LALAPG kappa) was produced in mammalian cells.
Background
The rat anti-mouse PD-1 monoclonal antibody (clone No. RMP1-14, rat IgG2a kappa) reacts with the mouse PD-1 protein (CD279 or programmed death-1) encoded by the mouse pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD 1 antibody and the anti-mouse PD L1 antibody which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The RMP1-14 antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein.
It is under investigation how the recombinant anti-mouse PD-1 / VEGFR-2 bispecific antibodies (RMP1-14.1 / DC101) behave different from the individual monoclonal antibodies and their combination.
Our recombinant anti-mouse PD-1 / VEGFR-2 bispecific antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse PD-1 antibody (hybridoma clone name or number: RMP1-14) and the rat anti-mouse VEGFR-2 antibody (hybridoma clone name or number: DC101).
Recombinant anti-HEL / HEL Bispecific Isotype Control Antibodies:
In vivo Grade Recombinant anti-HEL / HEL Mouse IgG1 Kappa Bispecific Isotype Control Antibody
In vivo Grade Recombinant anti-HEL / HEL Mouse IgG2a Kappa Bispecific Isotype Control Antibody
In vivo Grade Recombinant anti-HEL / HEL Mouse IgG2c Kappa Bispecific Isotype Control Antibody
Syd Labs provides the following anti-mouse PD1 (PD-L1) and VEGFR2 monoclonal antibodies:
In vivo grade recombinant anti-mouse PD-1 monoclonal antibodies (Clone RMP1-14.1)
In vivo grade recombinant anti-mouse PD 1 monoclonal antibodies (Clone 29F.1A12.1)
In vivo grade recombinant anti-mouse PD-L1 monoclonal antibodies (Clone 10F.9G2.1)
In vivo grade recombinant anti-mouse VEGFR2 monoclonal antibodies (Clone DC101)
Syd Labs provides the following anti-mouse PD-1 / VEGFR-2 bispecific antibodies:
In vivo grade recombinant anti-mouse PD 1 / VEGFR2 bispecific antibodies (Clone RMP1-14.1 / DC101)
In vivo grade recombinant anti-mouse PD-1 / VEGFR-2 bispecific antibodies (Clone 29F.1A12.1 / DC101)
Syd Labs provides the following anti-mouse PD-L1 / VEGFR-2 bispecific antibodies:
In vivo grade recombinant anti-mouse PDL1 / VEGFR-2 bispecific antibodies (Clone 10F.9G2.1 / DC101)
In Vivo Grade Recombinant Anti-mouse PD-1 / VEGFR-2 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone RMP1-14.1 / DC101) from: In Vivo Grade Recombinant Anti-mouse PD-1 / VEGFR-2 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone RMP1-14.1 / DC101): PA008026.m2cLA
