Anti-mouse CTLA-4 Monoclonal Antibody (Clone: 9D9) | PA007501.h1Fs

Catalog No.	PA007501.h1Fs
Product Name	Anti-mouse CTLA-4 Monoclonal Antibody (Clone: 9D9) | PA007501.h1Fs
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	cytotoxic T-lymphocyte associated antigen 4, cytotoxic T-lymphocyte antigen 4, CD152, CTLA4
Clone	9D9.
Isotype	Human IgG1 kappa.
Source/Host	The anti-mouse CTLA-4 monoclonal antibody (clone: 9D9) was produced in mammalian cells.
Specificity/Sensitivity	The recombinant 9D9 antibody specifically binds to mouse CTLA-4 protein.
Applications	Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).
Form Of Antibody	0.2 uM filtered solution, pH 7.4, containing 0.09% sodium azide.
Conjugate	Non-conjugated.
Purity	>95% by SDS-PAGE under reducing conditions.
Shipping	The Recombinant Anti-mouse CTLA-4 Monoclonal Antibody (Clone: 9D9), Human IgG1 Fc Silent Kappa is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, 2 to 8°C as supplied. Do not freeze it.
Note	Recombinant human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Order Offline	Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card.

Description

PA007501.h1Fs: Recombinant Anti-mouse CTLA-4 Monoclonal Antibody (Clone: 9D9), Human IgG1 Fc Silent Kappa

Recombinant Human IgG1 Monoclonal Antibody with Fc silent mutation.

Background

The 9D9 antibody blocks the mouse cytotoxic T lymphocyte antigen-4 (CTLA-4). Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.
Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is an inhibitory molecule that competes with the stimulatory CD28 for binding to B7 on antigen presenting cells. CTLA-4 and CD28 are both presented on the surface of T-cells.

Syd Labs provides the following research grade anti-CTLA-4 antibody biosimilars:

Ipilimumab Biosimilar, research grade, anti-human CTLA-4 monoclonal antibody
Tremelimumab Biosimilar, research grade, anti-human CTLA-4 monoclonal antibody

Recombinant CTLA-4 Proteins:

Biotinylated Human CTLA-4 Protein
Cynomolgus CTLA-4 Protein
Human CTLA-4 Protein

Recombinant Anti-mouse CTLA-4 Monoclonal Antibody (Clone: 9D9), Human IgG1 Fc Silent Kappa from: Recombinant Anti-mouse CTLA-4 Monoclonal Antibody (Clone: 9D9), Human IgG1 Fc Silent Kappa: PA007501.h1Fs Syd Labs

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