Anti-mouse CD28 Antibody for Flow Cytometry | PA007490.m2a
$60.00 – $120.00
Recombinant Mouse IgG1 isotype controls and Recombinant Human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
- Details & Specifications
- References
| Catalog No. | PA007490.m1 |
|---|---|
| Product Name | Recombinant Anti-mouse CD28 Monoclonal Antibody (Clone: PV-1), Mouse IgG2a Kappa |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | T-cell-specific surface glycoprotein CD28; TP44 |
| Clone | PV-1. |
| Isotype | Mouse IgG2a Kappa. |
| Source/Host | The anti-mouse CD28 antibody (clone: PV-1) for Flow Cytometry was produced in mammalian cells. |
| Specificity/Sensitivity | The recombinant PV-1 antibody for Flow Cytometry specifically binds to mouse CD28. |
| Applications | Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F). |
| Form Of Antibody | 0.2 uM filtered solution, pH 7.4, containing 0.09% sodium azide. |
| Conjugate | Non-conjugated. |
| Purity | >95% by SDS-PAGE under reducing conditions. |
| Shipping | The PV-1 antibody for Flow Cytometry is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, 2 to 8°C as supplied. Do not freeze it. |
| Note | Recombinant Mouse IgG2a isotype controls and Recombinant Human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card. |
Description
PA007490.m2a: Recombinant Anti-mouse CD28 Monoclonal Antibody (Clone: PV-1) for Flow Cytometry, Mouse IgG2a Kappa, In vivo Grade
Recombinant Mouse IgG2a Monoclonal Antibody for Flow Cytometry.
References of Anti-Mouse CD28 Monoclonal Antibody (Clone: PV-1)
1. CRK proteins selectively regulate T cell migration into inflamed tissues
Huang Y, et al.J Clin Invest. 2015 Mar 2;125(3):1019-32. PMID: 25621495
“Effector T cell migration into inflamed sites greatly exacerbates tissue destruction and disease severity in inflammatory diseases, including graft-versus-host disease (GVHD). T cell migration into such sites depends heavily on regulated adhesion and migration, but the signaling pathways that coordinate these functions downstream of chemokine receptors are largely unknown….”
2. Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice
Such J, et al.Mucosal Immunol. 2015 May;8(3):505-15. PMID: 25227984
“Mitogen-activated protein kinase (MAPK) phosphatases are dual-specificity phosphatases (DUSPs) that dephosphorylate phosphothreonine and phosphotyrosine residues within MAPKs. DUSP6 preferentially dephosphorylates extracellular signal-regulated kinases 1 and 2 (ERK1/2) rendering them inactive….”
3. CXCL13 antibody for the treatment of autoimmune disorders
Klimatcheva E, et al.BMC Immunol. 2015 Feb 12;16:6. PMID: 25879435
“Homeostatic B Cell-Attracting chemokine 1 (BCA-1) otherwise known as CXCL13 is constitutively expressed in secondary lymphoid organs by follicular dendritic cells (FDC) and macrophages. It is the only known ligand for the CXCR5 receptor, which is expressed on mature B cells, follicular helper T cells (Tfh), Th17 cells and regulatory T (Treg) cells….”
4. Novel aminotetrazole derivatives as selective STAT3 non-peptide inhibitors
Pallandre JR, et al.Eur J Med Chem. 2015 Oct 20;103:163-74. PMID: 26352675
“The development of inhibitors blocking STAT3 transcriptional activity is a promising therapeutic approach against cancer and inflammatory diseases. In this context, the selectivity of inhibitors against the STAT1 transcription factor is crucial as STAT3 and STAT1 play opposite roles in the apoptosis of tumor cells and polarization of the immune response….”
5. The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells
Bertin S, et al.Nat Immunol. 2014 Nov;15(11):1055-1063. PMID: 25282159
“TRPV1 is a Ca(2+)-permeable channel studied mostly as a pain receptor in sensory neurons. However, its role in other cell types is poorly understood….”
For more technical references or data sheets regarding the Recombinant Anti-Mouse CD28 Monoclonal Antibody (Clone: PV-1) formats, please contact our scientific support team at message@sydlabs.com or explore options via Syd Labs.
Syd Labs provides the following in vivo grade recombinant anti-mouse CD28 monoclonal antibodies:
Recombinant Anti-mouse CD28 monoclonal antibody (Clone: 37.51)
Recombinant Anti-mouse CD28 monoclonal antibody (Clone: PV-1)
Syd Labs provides the following in vivo grade recombinant anti-human CD28 monoclonal antibodies:
Recombinant Anti-human CD28 monoclonal antibody (Clone: CD28.2)
Recombinant Anti-human CD28 monoclonal antibody (Clone: 15E8)
Recombinant Anti-human CD28 monoclonal antibody (Clone: 9.3)
Recombinant Anti-human CD28 monoclonal antibody (Clone: CD28.3)
Syd Labs provides the following recombinant anti-human CD28 monoclonal antibodies for flow cytometry:
Recombinant Anti-human CD28 monoclonal antibody (Clone: CD28.2) for flow cytometry
Recombinant Anti-human CD28 monoclonal antibody (Clone: 15E8) for flow cytometry
Recombinant Anti-human CD28 monoclonal antibody (Clone: 9.3) for flow cytometry
Recombinant Anti-human CD28 monoclonal antibody (Clone: CD28.3) for flow cytometry
Anti-mouse CD28 Antibody (PV-1) for Flow Cytometry from: Recombinant Anti-mouse CD28 Monoclonal Antibody (Clone: PV-1), Mouse IgG2a Kappa: PA007490.m1 Syd Labs
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