Tusamitamab Biosimilar, Human CEACAM5 Monoclonal Antibody

Tusamitamab Biosimilar, Human CEACAM5 Monoclonal Antibody

$175.00$960.00

In stock

$175.00$960.00

Tusamitamab Biosimilar, Human CEACAM5 Monoclonal Antibody. The research grade tusamitamab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.

SKU: C109P
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Catalog No. C109P
Product NameTusamitamab Biosimilar, Human CEACAM5 Monoclonal Antibody
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms Carcinoembryonic Antigen-related Cell Adhesion Molecule 5
Summary Recombinant Humanized IgG1 Monoclonal Antibody.
Isotype Human IgG1 kappa.
Source/Host The anti-human CEACAM5 monoclonal antibody tusamitamab biosimilar was produced in mammalian cells.
Specificity/Sensitivity The in vivo grade tusamitamab biosimilar specifically binds to the CEACAM5 protein.
Form Of Antibody 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin < 1 EU per 1 mg of the protein by the LAL method.
Purity >95% by SDS-PAGE under reducing conditions and HPLC.
Shipping The research grade tusamitamab biosimilar is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
Note The research grade tusamitamab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Order Offline Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card.

Description

C109P: Tusamitamab Biosimilar, CEACAM5 Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.

Background

What is tusamitamab biosimilar research grade? Tusamitamab is a humanized IgG1-kappa monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) which is overexpressed in tumors including non-small cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC), and is an attractive target for therapies based on CAR-T cell or/and ADCs. Tusamitamab ravtansine (SAR408701) is an antibody-drug conjugate (ADC) combining a humanized monoclonal antibody and a potent cytotoxic maytansinoid derivative (DM4) inhibiting microtubule assembly. Tusamitamab biosimilar uses the same protein sequences as the therapeutic antibody tusamitamab.

Syd Labs provides the following research grade antibody biosimilars used in ADCs:
Tusamitamab biosimilar, research grade, anti-human CEACAM5 monoclonal antibody
Rovalpituzumab biosimilar, research grade, anti-human DLL3 monoclonal antibody
Trastuzumab biosimilar, research grade, anti-human HER2 monoclonal antibody
Cofetuzumab biosimilar, research grade, anti-human PTK7 monoclonal antibody
Ifinatamab biosimilar, research grade, anti-human B7-H3 (CD276) monoclonal antibody
Sacituzumab biosimilar, research grade, anti-human Trop-2 monoclonal antibody
Gemtuzumab biosimilar, research grade, anti-human CD33 monoclonal antibody
Polatuzumab biosimilar, research grade, anti-human CD79B monoclonal antibody
Cetuximab biosimilar, research grade, anti-human EGFR monoclonal antibody

Please remember our product information: Tusamitamab Biosimilar, Human CEACAM5 Monoclonal Antibody: C109P Syd Labs

Additional information

Ship from Country

USA

Size

1 mg, 20 mg, 5 mg

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